کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4225922 1609779 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Preoperative histological grading of meningiomas using apparent diffusion coefficient at 3T MRI
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی رادیولوژی و تصویربرداری
پیش نمایش صفحه اول مقاله
Preoperative histological grading of meningiomas using apparent diffusion coefficient at 3T MRI
چکیده انگلیسی

PurposeWe assessed whether a high b-value DWI at b = 4000 s/mm2 would discriminate the histopathological differentiation of the tumor grade of meningiomas, and also focused on the relationship between radiologic features and the tumor grade.Materials and methodsWe acquired DWI at 3T with b = 1000 and b = 4000 s/mm2 in 77 patients (42, 31 and 4 patients were WHO grades I (G1), II (G2), and III (G3), respectively). The apparent diffusion coefficient (ADC) was measured by placing multiple regions of interest (ROIs) on ADC maps. The ADC values of each tumor were determined preoperatively from several ROIs, and expressed as the minimum (ADCMIN), mean (ADCMEAN), and maximum absolute values (ADCMAX). We evaluated the relationship between ADCs and histological findings, and assessed the radiologic features such as tumor location, tumor size, presence/absence of peritumoral edema, shape of the tumor, presence/absence of bone destruction or hyperplasia, status of contrast enhancement, presence/absence of calcification and cyst.ResultsADCs of the meningiomas were inversely correlated with the histological grade of meningiomas. According to results of the discriminant analysis, the apparent log likelihood value was greatest for ADCMIN at b = 4000. Furthermore, only the ADCMIN value at b = 4000 was significantly correlated with the histological grade of meningiomas when we performed a multiple logistic regression analysis to identify the significant independent factors such as shape of tumor, presence/absence of bone destruction, status of contrast enhancement, presence/absence of cyst and ADCMIN at b = 4000.ConclusionA meningioma with a low ADCMIN at a high b-value might imply a high-grade meningioma.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Radiology - Volume 82, Issue 4, April 2013, Pages 658–663
نویسندگان
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