کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4226498 1609792 2012 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Virtual non-contrast in second-generation, dual-energy computed tomography: Reliability of attenuation values
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی رادیولوژی و تصویربرداری
پیش نمایش صفحه اول مقاله
Virtual non-contrast in second-generation, dual-energy computed tomography: Reliability of attenuation values
چکیده انگلیسی

PurposeTo evaluate the reliability of attenuation values in virtual non-contrast images (VNC) reconstructed from contrast-enhanced, dual-energy scans performed on a second-generation dual-energy CT scanner, compared to single-energy, non-contrast images (TNC).Materials and methodsSixteen phantoms containing a mixture of contrast agent and water at different attenuations (0–1400 HU) were investigated on a Definition Flash-CT scanner using a single-energy scan at 120 kV and a DE-CT protocol (100 kV/SN140 kV). For clinical assessment, 86 patients who received a dual-phase CT, containing an unenhanced single-energy scan at 120 kV and a contrast enhanced (110 ml Iomeron 400 mg/ml; 4 ml/s) DE-CT (100 kV/SN140 kV) in an arterial (n = 43) or a venous phase, were retrospectively analyzed. Mean attenuation was measured within regions of interest of the phantoms and in different tissue types of the patients within the corresponding VNC and TNC images. Paired t-tests and Pearson correlation were used for statistical analysis.ResultsFor all phantoms, mean attenuation in VNC was 5.3 ± 18.4 HU, with respect to water. In 86 patients overall, 2637 regions were measured in TNC and VNC images, with a mean difference between TNC and VNC of −3.6 ± 8.3 HU. In 91.5% (n = 2412) of all cases, absolute differences between TNC and VNC were under 15 HU, and, in 75.3% (n = 1986), differences were under 10 HU.ConclusionsSecond-generation dual-energy CT based VNC images provide attenuation values close to those of TNC. To avoid possible outliers multiple measurements are recommended especially for measurements in the spleen, the mesenteric fat, and the aorta.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Radiology - Volume 81, Issue 3, March 2012, Pages e398–e405
نویسندگان
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