Spontaneous Regression of Infantile Hepatic Hemangioendothelioma

Many primary hepatic tumors such as the rare pediatric neoplasms can be evaluated by sonography. Infantile hepatic hemangioendothelioma (IHH), the most common hepatic benign vascular tumor in infancy, has an excellent prognosis and spontaneous involution within 6-8 months in most cases. A 25-day-old baby girl was admitted to the hospital due to nonbilious vomiting for 2 days. Sonography showed multiple hypoechoic masses in the liver, and abdominal computed tomography demonstrated multifocal hypervascular lesions that were characteristic of IHH. The patient was then treated with supportive care and discharged in a stable condition without medication. Serial follow-up sonographic examinations showed that the size of the masses decreased gradually. At the age of 11 months, a follow-up sonogram confirmed complete resolution of IHH. Sonography is a useful and convenient method for diagnosis and follow-up of IHH. Long-term follow-up is necessary for IHH, even if the lesions are in regression, to watch for rare but possible malignant transformation.