Abnormal Doppler Venous Waveforms in a Fetus with Pentalogy of Cantrell

We report a case of 20 weeks' gestation which was diagnosed as pentalogy of Cantrell (PC). The sonographic examination revealed part of the typical fetal anomalies, including ectopia cordis and hepato-omphalocele. Abnormal venous flow including reversed A-wave of ductus venosus (DV) and pulsatile umbilical vein and portal vein were identified by Doppler ultrasound. Fetal magnetic resonance imaging confirmed the diagnosis with additional findings of pleural effusion and increased nuchal thickness. The pregnancy was terminated by elective vaginal induction. The chromosomal karyotype of cord blood was 46, XY.