کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4233424 1411596 2016 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Application of diffusion-weighted imaging and dynamic susceptibility contrast perfusion-weighted imaging for ganglioglioma in adults: Comparison study with oligodendroglioma
ترجمه فارسی عنوان
استفاده از تصویربرداری با وزن متعادل و حساسیت پویا تصویربرداری برای گانگلیوژیلوما در بزرگسالان: مطالعه مقایسه ای با اولیگودندرولیوم
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی رادیولوژی و تصویربرداری
چکیده انگلیسی

SummaryBackground and purposeTo evaluate diffusion-weighted imaging (DWI) and dynamic susceptibility contrast perfusion-weighted imaging (DSC-PWI) of ganglioglioma (GG) compared with oligodendroglioma (ODG).Materials and methodsWe enrolled 36 patients with histopathologically confirmed GG (12 patients) or ODG (24 patients). The volumetric analyses of normalized ADC (nADC) and normalized CBV (nCBV) maps, tumor volume, and ratio of enhancing portion compared to the tumor volume were performed. The microvessel area (MVA) was analyzed by staining with the CD34 monoclonal antibody.ResultsGGs occurred more frequently in the temporal lobe than in the frontal lobe. GGs showed a smaller tumor volume, and higher ratio of enhancing portion per tumor volume than ODGs (P = .002, and P = .010, respectively). GGs also showed lower nADC values (1.055 ± 0.063 vs 1.204 ± 0.030, P = .021) and higher nCBV values (0.777 ± 0.032 vs 0.514 ± 0.025, P < .001) than ODGs. Among the parameters in the multivariate model, nCBV was the most significant factor for differentiating GGs and ODGs (P < .0001). GGs showed significantly higher MVAs than ODGs (0.48 ± 0.09 vs 0.24 ± 0.04, P = .025).ConclusionOur results suggest that GGs tend to have relatively smaller tumor volume with higher ratio of enhancing portions, lower nADC values, and higher nCBV values than ODGs. Among these parameters, measurement of nCBV, which is correlated with a higher MVA measurement in GGs, can be the most useful tool for differentiating GGs from ODGs.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Neuroradiology - Volume 43, Issue 5, October 2016, Pages 331–338
نویسندگان
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