کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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4233671 | 1282767 | 2014 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: MRI abnormality of the pulvinar in patients with status epilepticus MRI abnormality of the pulvinar in patients with status epilepticus](/preview/png/4233671.png)
SummaryObjectiveRecently, magnetic resonance imaging (MRI) abnormalities of the pulvinar in patients with epilepsy have received greater attention, but their occurrence and features have not been fully elucidated. Therefore, we investigated the clinical and radiological features of patients with epilepsy who presented MRI abnormalities of the pulvinar.Patients and methodsWe retrospectively investigated 225 consecutive patients who came to our institute because of seizures and underwent an MRI within 24 h. The patients who exhibited pulvinar MRI abnormalities, their profile, seizure type, efficacy of medication, and chronological changes of MRI findings were examined.ResultsOut of the 225 patients who underwent MRI within 24 h of seizure, 17 exhibited MRI abnormalities of the pulvinar. All of these 17 patients presented status epilepticus. Bilateral pulvinar diffusion-weighted imaging (DWI) hyperintensity was observed in 3 patients and unilateral pulvinar DWI hyperintensity in the other 14. Out of these 14 patients, 7 exhibited DWI hyperintensity in the ipsilateral cerebral cortex, and 10 patients presented an old lesion due to stroke or trauma.ConclusionsOur results demonstrated that the involvement of the pulvinar in status epilepticus is more frequent than expected and consisted of unilateral or bilateral DWI hyperintensities that may completely normalize. These pulvinar MRI abnormalities possibly reflect the epileptogenic hyperexcitation of different cortical areas through their connections with the pulvinar.
Journal: Journal of Neuroradiology - Volume 41, Issue 4, October 2014, Pages 220–226