کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4250804 | 1411647 | 2016 | 22 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Bifunctional Gallium-68 Chelators: Past, Present, and Future
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
رادیولوژی و تصویربرداری
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
This article reviews the development of bifunctional chelates for synthesising 68Ga radiopharmaceuticals. It structures the chelates into groups of macrocycles, nonmacrocycles, and chimeric derivatives. The most relevant bifunctional chelates are discussed in chelate structure, parameters of 68Ga-labeling, and stability of the 68Ga-chelate complexes. Furthermore those derivatives are included, where 67Ga was applied instead of 68Ga. A particular feature discussed is the ability of certain bifunctional chelate structures to function in kit-type preparation of the 68Ga radiopharmaceuticals. Currently, nonmacrocyclic and chimeric derivates attract particular attention such as THP-derivates and DATA-derivates.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Nuclear Medicine - Volume 46, Issue 5, September 2016, Pages 373–394
Journal: Seminars in Nuclear Medicine - Volume 46, Issue 5, September 2016, Pages 373–394
نویسندگان
Philipp Spang, Christian Herrmann, Frank Roesch,