کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4410302 1307538 2012 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Stability considerations of aspartame in the direct analysis of artificial sweeteners in water samples using high-performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS)
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست شیمی زیست محیطی
پیش نمایش صفحه اول مقاله
Stability considerations of aspartame in the direct analysis of artificial sweeteners in water samples using high-performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS)
چکیده انگلیسی

A HPLC–MS/MS method is presented for the simultaneous determination of frequently used artificial sweeteners (ASs) and the main metabolite of aspartame (ASP), diketopiperazine (DKP), in environmental water samples using the direct-injection (DI) technique, thereby achieving limits of quantification (LOQ) of 10 ng L−1. For a reliable quantification of ASP pH should be adjusted to 4.3 to prevent formation of the metabolite. Acesulfame (ACE), saccharin (SAC), cyclamate (CYC) and sucralose (SUC) were ubiquitously found in water samples. Highest concentrations up to 61 μg L−1 of ACE were found in wastewater effluents, followed by surface water with concentrations up to 7 μg L−1, lakes up to 600 ng L−1 and groundwater and tap water up to 70 ng L−1. The metabolite DKP was only detected in wastewater up to 200 ng L−1 and at low detection frequencies.


► Direct injection HPLC–MS/MS used for measuring artificial sweeteners (ASs) in water.
► Degradation kinetics of aspartame (ASP) at different pH was performed.
► Diketopiperazine (DKP), represents main transformation product of ASP in water.
► DKP present only in wastewater effluents at low frequencies.
► Determination of levels of AS in different environmental water samples.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chemosphere - Volume 88, Issue 5, July 2012, Pages 563–569
نویسندگان
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