کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4412292 1307632 2009 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Distribution of persistent organochlorine pollutants in maternal and foetal tissues: Data from an Italian polluted urban area
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست شیمی زیست محیطی
پیش نمایش صفحه اول مقاله
Distribution of persistent organochlorine pollutants in maternal and foetal tissues: Data from an Italian polluted urban area
چکیده انگلیسی

This study was designed to evaluate both levels and distributions of organochlorine pollutants in placenta and other maternal–foetal tissues, from women resident in an Italian highly industrialized urban area with demonstrated PCB pollution.To this end, 30 polychlorinated biphenyl congeners (PCBs), p,p′-dichlorodiphenyltrichloroethane (p,p′-DDT), p,p′-dichlorodiphenyldichloroethylene (p,p′-DDE) and hexachlorobenzene (HCB), were determined in placenta, both maternal and cord blood serum and adipose tissue of Caucasian pregnant women (n = 70) undergoing to programmed caesarean delivery.Median placental concentrations of PCBs, p,p′-DDE and HCB (0.89 ng g−1, 0.63 ng g−1 and 0.19 ng g−1 on wet tissue weight basis, respectively), were lower than previously published data. p,p′-DDT could be detected in most of adipose tissue samples, but very rarely in the other compartments.Distributions of investigated compounds in biological matrices showed significant relationships, confirming their transplacental transfer. It is worthy of note that HCB tended to be transferred more easily from maternal to foetal tissues.Maternal serum levels of these pollutants can allow a reliable estimation of organochlorine compound body burden, and can be useful markers of prenatal exposure, given their relationships with placental and umbilical cord serum levels.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chemosphere - Volume 76, Issue 6, August 2009, Pages 747–754
نویسندگان
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