کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4413077 | 1307663 | 2008 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Absorption of nitro-polycyclic aromatic hydrocarbons by biomembrane models: Effect of the medium lipophilicity Absorption of nitro-polycyclic aromatic hydrocarbons by biomembrane models: Effect of the medium lipophilicity](/preview/png/4413077.png)
To demonstrate the relationship between the structure of nitro-polycyclic aromatic hydrocarbons and their effect on biomembranes, we have investigated the influence of three structurally different nitro-polycyclic aromatic hydrocarbons, 2-nitrofluorene, 2,7-dinitrofluorene and 3-nitrofluoranthene, on the thermotropic behavior of dimyristoylphosphatidylcholine multilamellar vesicles, used as biomembrane models, by means of differential scanning calorimetry. The obtained results indicate that the studied nitro-polycyclic aromatic hydrocarbons affected the thermotropic behavior of multilamellar vesicles to various extents, modifying the pretransition and the main phase transition peaks and shifting them to lower temperatures. The effect of the aqueous and lipophilic medium on the absorption process of these compounds by the biomembrane models has been also investigated revealing that the process is hindered by the aqueous medium but strongly allowed by the lipophilic medium.
Journal: Chemosphere - Volume 73, Issue 7, October 2008, Pages 1108–1114