A comparative study of Saccharomyces cerevisiae sensitivity against eight yeast species sensitivities to a range of toxicants

The growth inhibition bioassay showed that all yeast species had similar dose-response curves for the five organic fungicides and two environmental samples used. However, two yeast species, Trichosporon dulcitum and Pseudozyma fusiformata, were a great deal more sensitive than all others to CuSO4 and K2Cr2O7 while S. cerevisiae was the most tolerant to these chemicals. S. cerevisiae, however, showed similar sensitivity as other species to all toxicants in the resorufin fluorescence inhibition bioassay. It can therefore be used as a representative yeast species for assessing effects of environmental contaminants to non-target fungi and in the screening of chemical libraries for fungicidal activity.