کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4502407 1624165 2013 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The ancestral selection graph under strong directional selection
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم کشاورزی و بیولوژیک (عمومی)
پیش نمایش صفحه اول مقاله
The ancestral selection graph under strong directional selection
چکیده انگلیسی

The ancestral selection graph (ASG) was introduced by  Neuhauser and Krone (1997) in order to study populations of constant size which evolve under selection. Coalescence events, which occur at rate 1 for every pair of lines, lead to joint ancestry. In addition, splitting events in the ASG at rate αα, the scaled selection coefficient, produce possible ancestors, such that the real ancestor depends on the ancestral alleles. Here, we use the ASG in the case without mutation in order to study fixation of a beneficial mutant. Using our main tool, a reversibility property of the ASG, we provide a new proof of the fact that a beneficial allele fixes roughly in time (2logα)/α(2logα)/α if αα is large.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Theoretical Population Biology - Volume 87, August 2013, Pages 25–33
نویسندگان
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