کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4908972 | 1427092 | 2017 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Gellan microgels produced in planar microfluidic devices
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Gellan microgels produced in planar microfluidic devices Gellan microgels produced in planar microfluidic devices](/preview/png/4908972.png)
چکیده انگلیسی
Microgels were obtained from the droplets gelation of a water-in-oil emulsion containing gellan in the aqueous phase. Gellan gum (0.6% w/w) and calcium acetate (0.5 and 2.0% w/w) as gelling agent were used to produce the microgels. The effect of the continuous phase flow rate and salt concentration on the particle size and size polydispersity of the gellan microgels was evaluated, as well as microchannels configuration for encapsulation of hydrophilic compounds in these particles using planar microfluidics devices. The microgels exhibited uniform and spherical shape. A highly monodisperse particle size distribution was observed showing coefficient of variation below 5% and average size ranging from 63 to 113 μm. Increasing salt concentration caused an increase of the mean particle diameter and a decrease of the size polydispersity. However at high salt concentration the continuous flow rate did not exert significant effect on the microgel size since average size ranged from 106 to 113 μm. A potential use of gellan microgels as encapsulating matrix of active compounds was evaluated by adding a hydrophilic dye, Rhodamine B, in the aqueous phase. Results showed good retention capacity of the dye and stability over time of storage, indicating that microgels obtained by microfluidics technique may be used for the encapsulation of hydrophilic compounds, including those sensitive to temperature and pressure, as well as in drug delivery.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Food Engineering - Volume 209, September 2017, Pages 18-25
Journal: Journal of Food Engineering - Volume 209, September 2017, Pages 18-25
نویسندگان
Ana LetÃcia Rodrigues Costa, Andresa Gomes, Fernanda Yumi Ushikubo, Rosiane Lopes Cunha,