Depression severity and quality of life of qualified and unqualified patients with a mood disorder for a research study targeting anhedonia in a clinical sample

Depressive mood and anhedonia are highly correlated. Screening patients with a mood disorder and an overall moderate depressive severity is a cost-effective approach for a study targeting anhedonia, especially for a study requiring ≥ moderate severity of anhedonia. However, 1/3 of the unqualified patients will have ≥ moderate overall depressive symptoms and poor quality of life.