کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4933281 | 1433793 | 2017 | 35 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Hyperarousal during sleep in untreated primary insomnia sufferers: A polysomnographic study
ترجمه فارسی عنوان
بیش از حد در طول خواب در مبتلایان به بی خوابی اولیه درمان نشده: یک مطالعه پلیسومنوگرافی
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کلمات کلیدی
ACTHSPTREMDSM IV-TRTSTBDISWSSOPISI - آی اس آیgamma-aminobutyric acid - اسید گاما آمینو بوتیریکSleep efficiency - بازده خوابPrimary insomnia - بی خوابی اولیهWake after sleep onset - بیدار شدن بعد از خوابHyperarousal - بیش از حدSleep latency - تاخیر خوابrapid eye movement - حرکت سریع چشمslow-wave sleep - خواب آهستهsleep period time - زمان خواب خوابtotal sleep time - زمان خواب کلInsomnia severity index - شاخص شدت بی خوابیHPA - میلی بار یا هکتوپاسکالadrenocorticotropic hormone - هورمون adrenocorticotropichypothalamic-pituitary-adrenal - هیپوتالاموس-هیپوفیز-آدرنالWASO - واسهPathophysiology - پاتوفیزیولوژیBeck Depression Inventory - پرسشنامه افسردگی بکPolysomnography - پلی سومنوگرافیGABA - گابا
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
روانپزشکی بیولوژیکی
چکیده انگلیسی
Because some evidence favors the hyperarousal model of insomnia, we sought to learn more about the dynamics of this phenomenon during sleep. Polysomnographic data from 30 normative subjects and 86 untreated primary insomnia sufferers recruited from the database of the sleep laboratory were studied for whole nights and in terms of thirds of the night. Untreated primary insomnia sufferers had an increased sleep latency and excess of WASO, together with a deficit in REM and NREM sleep during the entire night. In terms of thirds of the night, they presented a major excess of WASO during the first and last thirds of the night but an excess of lesser importance during the middle third. A deficit in SWS was found during the first third of the night, but for REM, the deficit was present during both the first and last thirds. Primary insomnia sufferers had no SWS or REM deficit during the second third of the night. We found that the hyperarousal phenomenon occurs mainly during the sleep-onset period of the first and last thirds of the night and is less important during the middle third. These results open new avenues for understanding the pathophysiology of primary insomnia.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychiatry Research - Volume 253, July 2017, Pages 71-78
Journal: Psychiatry Research - Volume 253, July 2017, Pages 71-78
نویسندگان
Matthieu Hein, Christelle Senterre, Jean-Pol Lanquart, Xavier Montana, Gwénolé Loas, Paul Linkowski, Philippe Hubain,