کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5137528 | 1494538 | 2017 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Virgin olive oil enriched with its own phenolic compounds or complemented with thyme improves endothelial function: The potential role of plasmatic fat-soluble vitamins. A double blind, randomized, controlled, cross-over clinical trial
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کلمات کلیدی
Plasminogen activator inhibitor type IGPXICAM-1MCP-1IrhPAI-1hsCRPNOx - NOXUPLC-MS/MS - UPLC-MS / MSPhenolic compounds - ترکیبات فنولیTriglycerides - تریگلیسریدIntercellular cell adhesion molecule - مولکول چسبندگی سلول بین سلولیNitric oxide - نیتریک اکسیدmonocyte chemotactic protein - پروتئین chemotactic monocytehigh sensitivity C-reactive protein - پروتئین واکنش پذیر C با حساسیت بالاhigh performance liquid chromatography - کروماتوگرافی مایع با کارایی بالاHPLC - کروماتوگرافی مایعی کاراInternational Conference of Harmonization - کنفرانس بین المللی هماهنگیglutathione peroxidase - گلوتاتیون پراکسیداز
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Virgin olive oil enriched with its own phenolic compounds or complemented with thyme improves endothelial function: The potential role of plasmatic fat-soluble vitamins. A double blind, randomized, controlled, cross-over clinical trial Virgin olive oil enriched with its own phenolic compounds or complemented with thyme improves endothelial function: The potential role of plasmatic fat-soluble vitamins. A double blind, randomized, controlled, cross-over clinical trial](/preview/png/5137528.png)
چکیده انگلیسی
The aim of the present study was to assess whether different functional virgin olive oils (FVOOs) with varying phenolic compounds (PC) could protect the plasmatic fat-soluble vitamins, which in turn could improve the endothelial function. In order to select the optimal phenolic dose in the improvement of ischemic reactive hyperemia (IRH), a dose-response study (n = 12, healthy subjects) was performed and the enrichment of 500 mg PC/kg oil was selected. In a 3-week cross-over sustained study (n = 33 hypercholesterolemic subjects), the consumption of 25 mL/day of two phenol-enriched olive oils (one enriched with its own PC and another combined with thyme PC) increased IRH and plasma concentrations of retinol, β-cryptoxanthin and α-tocopherol, compared to a control virgin olive oil. A positive post-intervention correlation was observed for IRH values and HDL-c, β-cryptoxanthin, lutein and α-tocopherol. Results suggest that preservation of plasmatic fat-soluble vitamins by PC from FVOOS could partially explain the endothelial function benefits.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Functional Foods - Volume 28, January 2017, Pages 285-292
Journal: Journal of Functional Foods - Volume 28, January 2017, Pages 285-292
نویسندگان
Rosa-M. Valls, Marta Farrà s, Anna Pedret, Sara Fernández-Castillejo, Ãrsula Catalán, Marta Romeu, Montse Giralt, Guillermo-T. Sáez, Montserrat Fitó, Rafael de la Torre, MarÃa-Isabel Covas, MarÃa-José Motilva, Rosa Solà , Laura Rubió,