کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5137595 | 1494530 | 2017 | 13 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Chemical composition and in vitro chemoprevention assessment of Eugenia jambolana Lam. (Myrtaceae) fruits and leaves
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
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چکیده انگلیسی
Eugenia jambolana has been used as an antioxidant, anti-inflammatory and antidiabetic. This study performed a chemical and chemopreventive screening of extracts and fractions from leaves and fruits from Eugenia jambolana. The purification of the crude extract from leaves afforded two known flavonoids, tricetin-4â²-O-α-l-rhamnopyranoside (1), and myricitrin (2), whereas the purification of crude extract from fruits afforded one anthocyanin, malvidin-3-O-gentibioside (3). Additionally, seven anthocyanins were tentatively identified. The antigenotoxicity results showed that post-treatment with extracts and fractions mitigated the damage induced by hydrogen peroxide. In assessing the antimutagenicity, the samples were able to reduce the frequency of micronucleus formation for both pre-treatment and post-treatment. Also, extracts and fractions promoted the induction of quinone reductase activity. Such extracts and fractions were able to induce detoxifying enzymes and reverse DNA damage, an essential balance for its applicability as a chemopreventive agent.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Functional Foods - Volume 36, September 2017, Pages 490-502
Journal: Journal of Functional Foods - Volume 36, September 2017, Pages 490-502
نویسندگان
Alessandra C. Dametto, Daniele Agustoni, Thais F. Moreira, Carenina V. Plaza, Aline M. Prieto, Tarsia G.A. Silva, Felipe O. Souza, Nivaldo Boralle, Juliana Maria Sorbo, Dulce H.S. Silva, Christiane P. Soares,