کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5141614 | 1495877 | 2017 | 41 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Single-cell analysis by ambient mass spectrometry
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Single-cell analysis by ambient mass spectrometry Single-cell analysis by ambient mass spectrometry](/preview/png/5141614.png)
چکیده انگلیسی
Analysis of chemicals at single-cell level plays an important role in the investigation of cell genomics, transcriptomics, proteomics, and metabolomics, and it also provides significant insight in life science, biological, medicinal, pharmacological, pathological, and toxicological studies. As a newly developed technique, ambient mass spectrometry has been proven to be a powerful tool for rapid, direct, and straightforward analysis of cellular and subcellular ingredients and metabolites under ambient and open-air conditions. In this review article, we discuss the fields of ambient mass spectrometry for analysis of single cells that have been published to date. Different strategies for application of various ambient ionization techniques to achieve single-cell mass spectrometric analysis are categorized and commented, and the typical analyses and applications are summarized and discussed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: TrAC Trends in Analytical Chemistry - Volume 90, May 2017, Pages 14-26
Journal: TrAC Trends in Analytical Chemistry - Volume 90, May 2017, Pages 14-26
نویسندگان
Yunyun Yang, Yanying Huang, Junhui Wu, Ning Liu, Jiewei Deng, Tiangang Luan,