Chitosan encapsulation of essential oil “cocktails” with well-defined binary Zn(II)-Schiff base species targeting antibacterial medicinal nanotechnology

Targeting the ever-increasing multi-resistance properties of infectious pathogens, novel hybrid chitosan-based antimicrobial nanomaterials were developed. Loaded with well-defined structure-specific/activity-selective cocktails of Zn(II)-Schiff complex and Greek-origin essential oils, the novel loaded nanoparticles demonstrated distinct delivery-release profiles, commensurably optimized against Gram-positive/negative bacteria, thereby aiding the development of efficient natural origin antibacterial nanotechnology.212