New dibutyltin(IV) ladders: Syntheses, structures and, optimization and evaluation of cytotoxic potential employing A375 (melanoma) and HCT116 (colon carcinoma) cell lines in vitro

Dibutyltin(IV) ladders containing a tetrametallic core induces program cell death without necrosis or disturbing primary cells' activities. Moreover, the compounds were found to alter the membrane fluidity and micro-viscosity of cells and increases cell death possibly by interfering with the growth factor-mediated cell signaling.105