Challenges in the development of an M4 PAM preclinical candidate: The discovery, SAR, and in vivo characterization of a series of 3-aminoazetidine-derived amides

Challenges in the development of an M4 PAM preclinical candidate: The discovery, SAR, and in vivo characterization of a series of 3-aminoazetidine-derived amides

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 27, Issue 13, 1 July 2017, Pages 2990-2995

James C. Tarr, Michael R. Wood, Meredith J. Noetzel, Jeanette L. Bertron, Rebecca L. Weiner, Alice L. Rodriguez, Atin Lamsal, Frank W. Byers, Sichen Chang, Hyekyung P. Cho, Carrie K. Jones, Colleen M. Niswender, Michael W. Wood, Nicholas J. Brandon,