Optimization of M4 positive allosteric modulators (PAMs): The discovery of VU0476406, a non-human primate in vivo tool compound for translational pharmacology

Optimization of M4 positive allosteric modulators (PAMs): The discovery of VU0476406, a non-human primate in vivo tool compound for translational pharmacology

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 27, Issue 11, 1 June 2017, Pages 2296-2301

Bruce J. Melancon, Michael R. Wood, Meredith J. Noetzel, Kellie D. Nance, Eileen M. Engelberg, Changho Han, Atin Lamsal, Sichen Chang, Hyekyung P. Cho, Frank W. Byers, Michael Bubser, Carrie K. Jones, Colleen M. Niswender, Michael W. Wood,