Synthesis and evaluation of 4,6-disubstituted pyrimidines as CNS penetrant pan-muscarinic antagonists with a novel chemotype

Synthesis and evaluation of 4,6-disubstituted pyrimidines as CNS penetrant pan-muscarinic antagonists with a novel chemotype

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 27, Issue 11, 1 June 2017, Pages 2479-2483

Aaron M. Bender, Rebecca L. Weiner, Vincent B. Luscombe, Hyekyung P. Cho, Colleen M. Niswender, Darren W. Engers, Thomas M. Bridges, P. Jeffrey Conn, Craig W. Lindsley,