Difluorocyclobutylacetylenes as positive allosteric modulators of mGluR5 with reduced bioactivation potential

Difluorocyclobutylacetylenes as positive allosteric modulators of mGluR5 with reduced bioactivation potential

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 26, Issue 24, 15 December 2016, Pages 5871-5876

Andrew P. Degnan, Darrell Maxwell, Anand Balakrishnan, Jeffrey M. Brown, Amy Easton, Michael Gulianello, Umesh Hanumegowda, Melissa Hill-Drzewi, Regina Miller, Kenneth S. Santone, Arun Senapati, Eric E. Shields, Digavalli V. Sivarao, Ryan Westphal,