کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5160360 | 1501680 | 2017 | 37 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis, characterization and biological studies of copper(II) complexes with 2-aminobenzimidazole derivatives
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Novel series of four copper(II) complexes with 2-aminobenzimidazole derivatives (obtained from the Knoevenagel condensate of acetylacetone (obtained from acetylacetone and halogen substituted benzaldehydes) and 2-aminobenzimidazole) were synthesized. They were structurally characterized using elemental analysis, molar conductance, FAB mass, FT- IR, 1H & 13C-NMR, UV-Vis., and EPR techniques. On the basis of analytical and spectral studies, the distorted square planar geometry was assigned for all the complexes. The antibacterial screening of the ligands and their copper complexes indicated that all the complexes showed higher anti microbial activities than the free ligands. Superoxide dismutase and antioxidant activities of the copper complexes have also been performed. In the electrochemical technique, the shift in ÎEp, E1/2 and Ipc values were explored for the interaction of the complexes with CT-DNA. During the electrolysis process, the present ligand system stabilizes unusual oxidation state of copper in the complexes. It is believed that the copper complexes with curcumin analogs may enhance chemotherapeutic behavior.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Molecular Structure - Volume 1137, 5 June 2017, Pages 17-26
Journal: Journal of Molecular Structure - Volume 1137, 5 June 2017, Pages 17-26
نویسندگان
J. Joseph, A. Suman, K. Nagashri, R. Selwin Joseyphus, Nisha Balakrishnan,