Botryane, noreudesmane and abietane terpenoids from the ascomycete Hypoxylon rickii

Ten terpenoids, among those seven novel natural products, were isolated from cultures of the tropical ascomycete Hypoxylon rickii (Xylariaceae). Their structures were elucidated using 2D NMR and HRESIMS. The new compounds belong to the botryane, 14-noreudesmane and abietane types. Compounds 1, 2, 3, 7, and 10 showed cytotoxic effects against murine cells.