Flavonols and an oxychromonol from Piliostigma reticulatum

Chemical investigation of Piliostigma reticulatum leaves lead to the isolation of a chromone, three new and three known flavonoids, namely, 1, C-methyl-p-phenoxychromonol (Piliostigmol), 2, 6,8-di-C-methylquercetin-3,3′,7-trimethyl ether, 3, 6,8-di-C-methylquercetin-3,3′-dimethyl ether, 4, 3′,6,8-tri-C-methylquercetin-3,7-dimethyl ether, 5, 6-C-methylquercetin-3-methyl ether, 6, 6,8-di-C-methylkaempferol-3-methyl ether and 7, 6-C-methylquercetin-3,3′,7-trimethyl ether, respectively. The compounds showed variable cytotoxic and antimicrobial activities.