Cytotoxic and antiplasmodial substances from marine-derived fungi, Nodulisporium sp. and CRI247-01

Nodulisporacid A (1) and vermelhotin (5) were isolated from marine-derived fungi. Esters of nodulisporacid A (1) and vermelhotin (5) exhibited cytotoxic activity. 1 and 5 exhibited moderate antiplasmodial activity.