Bioactive withanolides from Withania obtusifolia

- One new and six known withanolides were isolated from Withania obtusifolia.
- The compounds were evaluated for cytotoxicity using a human cancer cell panel.
- The compounds were evaluated for antimicrobial activity.
- In vitro activity of withaferin A on 5α-reductase was investigated.
- In vitro activity of withaferin A on 17β-hydroxysteroid dehydrogenase.