کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5177182 1380851 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Dihydronaphthalenones from the endophytic fungus Botryosphaeria sp. BCC 8200
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Dihydronaphthalenones from the endophytic fungus Botryosphaeria sp. BCC 8200
چکیده انگلیسی

Five new dihydronaphthalenones (1, 2a/2b, 3a/3b), four of which were isolated as two inseparable mixtures of isomers, together with two known compounds, 7-hydroxy-2-(2-hydroxypropyl)-5-methylchromone (4) and siderin (5), were identified as secondary metabolites of the endophytic fungus Botryosphaeria sp. BCC 8200. The structures were elucidated by interpretation of NMR spectroscopic and mass spectrometry data. Compounds 2a/2b, 3a/3b, and 5 exhibited weak cytotoxic activities against cancer cell lines.

New dihydronaphthalenone derivatives, 3,4-dihydro-3-(2-oxo-propyl)-3(ξ),6,8-trihydroxy-1(2H)-naphthalenone (1), 3,4-dihydro-3-(2(ξ)-hydroxypropyl)-3(ξ),6,8-trihydroxy-1(2H)-naphthalenone (2a/2b; 2.5:1 mixture of diastereomers), and 3,4-dihydro-3-(4(ξ)-hydroxy-2-oxo-pentyl)-3(ξ),6,8-trihydroxy-1(2H)-naphthalenone (3a/3b; 5:1 mixture of diastereomers) were isolated from the endophytic fungus Botryosphaeria sp. BCC 8200.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Phytochemistry Letters - Volume 2, Issue 4, 19 November 2009, Pages 207-210
نویسندگان
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