کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5208375 1382569 2013 22 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Biomedical applications and colloidal properties of amphiphilically modified chitosan hybrids
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Biomedical applications and colloidal properties of amphiphilically modified chitosan hybrids
چکیده انگلیسی
Chitosan is among the most abundant biopolymers on earth and has been either used or exhibited potential in a wide variety of industrial and biomedical applications. With the advancement of materials technologies, chitosan has been chemically modified to self-assemble into nanoarchitectures that are usable in advanced biomedical applications, such as drug nanocarriers, macroscopic injectables, tissue-engineering scaffolds, and nanoimaging agents. Colloidal amphiphilically modified chitosan (AMC) is a relatively recent material receiving increased attention with numerous publications addressing the medical advantages of specific systems. To date, many reviews have focused on the synthesis and biomedical properties of chitosan-based biomaterials, but a comprehensive study focusing on the colloidal properties of AMC in relation to biomedical performance appears to be lacking. This review provides a survey of the field, critically reviewing the colloidal properties and biomedical performance of AMC systems, such as nanoparticle drug delivery systems and macroscopic medical devices. Finally, the future development, market potential, and clinical implications of these promising colloidal-structured biomaterials are summarised.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Progress in Polymer Science - Volume 38, Issue 9, September 2013, Pages 1307-1328
نویسندگان
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