کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5208827 1382613 2008 39 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Modern trends in polymer bioconjugates design
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Modern trends in polymer bioconjugates design
چکیده انگلیسی

This review describes recent changes and progress in the field of polymer bioconjugation (i.e. covalent attachment of synthetic polymers to biological entities such as nucleic acids, oligopeptides, proteins, enzymes, carbohydrates, viruses or cells). This important field of research has evolved radically during the last decade. Polymer bioconjugates have been initially developed by biochemists and have been for many years studied practically exclusively for bio-medical applications. However, within the last few years, these novel class of macromolecules have been shown to be useful in many other emerging areas of materials science. Therefore, the synthesis of polymer bioconjugates became rather suddenly a central topic in polymer chemistry. For instance, modern synthetic methods such as controlled radical polymerization, ring opening metathesis polymerization or “click” chemistry have been recently proven to be extremely versatile tools for preparing tailor-made polymer bioconjugates. These novel synthetic trends are discussed in details in the present manuscript.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Progress in Polymer Science - Volume 33, Issue 1, January 2008, Pages 1-39
نویسندگان
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