2,6-Diamination of substituted pyridines via heterogeneous Chichibabin reaction

A series of methyl, tert-butyl, phenyl, pyridinyl, and hydroxyl substituted 2,6-diaminopyridines are prepared via the heterogeneous Chichibabin amination in neat mineral oil at temperatures up to 215 °C with an overall reaction time of 3-5 h.