An efficient chemoselective etherification of phenols in polyfunctional aromatic compounds

A simple and efficient chemoselective alkylation of phenols in polyfunctional aromatic compounds with different alkyl halides in the presence of K2CO3/TBAB is reported. The method is successful with various hydroxy aromatic acids or oximes possessing other functional groups.

A simple method for chemoselective phenol alkylation with different phenolic substrates and alkyl halides is described using TBAB as catalyst.