کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5279243 1385621 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Palladium-catalysed direct 3- or 4-arylation of thiophene derivatives using aryl bromides
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Palladium-catalysed direct 3- or 4-arylation of thiophene derivatives using aryl bromides
چکیده انگلیسی

The palladium-catalysed direct 3- or 4-arylation of 2,5-disubstituted thiophenes using aryl bromides gives a simple access to a variety of 3- or 4-arylthiophene derivatives. Moderate to good yields of 3-arylated thiophenes were obtained using 2,5-dimethylthiophene. In the presence of unsymmetrically disubstituted, 2-acetyl-5-methylthiophene, a regioselective arylation on carbon 4 of thiophene was observed. This reaction provides only HX associated to the base as by-product and reduces the number of steps to prepare these compounds.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 50, Issue 23, 10 June 2009, Pages 2778-2781
نویسندگان
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