Microwave-promoted synthesis of chiral pyridinium salts

The synthesis of several chiral pyridinium salts via Zincke's reaction can be easily accomplished by domestic microwave oven irradiation. Yield enhancements, reduction of reaction time, and less racemization were observed under microwave heating when compared to conventional heating in similar conditions.

The synthesis of several chiral pyridinium salts via Zincke's reaction can be easily accomplished by microwave oven irradiation. Yield enhancements, shorter reaction times, and less racemization were observed under microwave heating when compared to conventional heating.