کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5372331 1503980 2007 14 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Collision induced spatial organization of microtubules
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی تئوریک و عملی
پیش نمایش صفحه اول مقاله
Collision induced spatial organization of microtubules
چکیده انگلیسی

The dynamic behavior of microtubules in solution can be strongly modified by interactions with walls or other structures. We examine here a microtubule growth model where the increase in size of the plus-end is perturbed by collisions with other microtubules. We show that such a simple mechanism of constrained growth can induce ordered structures and patterns from an initially isotropic and homogeneous suspension. We find that microtubules self-organize locally in randomly oriented domains that grow and compete with each other. A weak orientation bias, similar to the one induced by gravity or cellular boundaries is enough to influence the domain growth direction, eventually leading to a macroscopic sample orientation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biophysical Chemistry - Volume 128, Issues 2–3, July 2007, Pages 231-244
نویسندگان
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