Novel ratio fluorescence probes for selectively detecting zinc ion based on Y-type quinoxaline framework

- Several novel Y-type quinoxaline probes were developed for zinc ion detecting.
- They showed significant fluorescent turn-on and ratiometric detection of Zn2+.
- These probes displayed high selectivity for zinc ion.
- A new receptor for Zn2+ based on 2,3-dipyridylquinoxaline segment was exploited.

Several simple Y-type 2, 3-di(2′-pyridyl or quinoyl)quinoxaline derivatives had been synthesized, which is firstly utilized for detecting zinc ion as the receptor and fluorophore. They showed significant fluorescent turn-on and ratiometric detection of Zn2+ with red shift and remarkable fluorescence ratio enhancement. In addition, these probes displayed high selectivity for zinc ion over other relevant ions. Theoretical calculations were carried out to investigate the recognition mechanism of the intramolecular charge transfer.

Several simple Y-type 2, 3-di(2′-pyridyl or quinoyl)quinoxaline derivatives had been synthesized, which is firstly utilized for detecting zinc ion as the receptor and fluorophore. They showed significant fluorescent turn-on and ratiometric detection of Zn2+ with red shift and remarkable fluorescence ratio enhancement. In addition, these probes displayed high selectivity for zinc ion over other relevant ions. Theoretical calculations were carried out to investigate the recognition mechanism of the intramolecular charge transfer.186