کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5398702 | 1505890 | 2016 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Sensitive and rapid chemiluminescence detection of propranolol based on effect of surface charge of gold nanoparticles
ترجمه فارسی عنوان
تشخیص حساسیت و سریع شیمی درمانی پروپرانولول براساس اثر بارگذاری سطح نانوذرات طلا
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کلمات کلیدی
پروپرانولول، شیمی معدنی، نانوذرات طلا، سطح شارژ،
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی تئوریک و عملی
چکیده انگلیسی
We report a label-free, gold nanoparticles (AuNPs)-based chemiluminescent method for propranolol assay. The method relies upon the catalytic activity of unmodified AuNPs on the luminol-H2O2 chemiluminescence (CL) reaction, and the interaction of unmodified AuNPs with propranolol. The surface charge property of AuNPs directly affects their catalytic performance for CL reaction, and the interaction of AuNPs with propranolol can change AuNPs׳ surface charge property and induce the AuNP aggregation, and after aggregation the catalytic activity of AuNPs on the luminol-H2O2 CL reaction is greatly enhanced. During the assay, no covalent functionalization of AuNPs is required. The assay is homogenous. The detection limit of propranolol (3Ï) was estimated to be as low as 6.6Ã10â12 g mLâ1, and the sensitivity was 4 orders of magnitude better than that of known CL methods for the detection of propranolol. This AuNPs-based CL method offers the advantages of being simple, cheap, rapid, and sensitive.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Luminescence - Volume 171, March 2016, Pages 238-245
Journal: Journal of Luminescence - Volume 171, March 2016, Pages 238-245
نویسندگان
Yingying Qi, Fu-Rong Xiu,