کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5399381 1505900 2015 49 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Designing hydrophobic sheet protected Eu(III)-tetracycline complex using long chain unsaturated fatty acid: Efficient 'antenna effect' in aqueous medium
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی تئوریک و عملی
پیش نمایش صفحه اول مقاله
Designing hydrophobic sheet protected Eu(III)-tetracycline complex using long chain unsaturated fatty acid: Efficient 'antenna effect' in aqueous medium
چکیده انگلیسی
We have designed a novel ternary system consisting of Tetracycline hydrochloride (TC), Eu(III) and unsaturated long chain fatty acid (Oleic acid, α-Linolenic acid) in aqueous buffer at physiological pH of 7.2. The systems exhibit highly efficient 'antenna effect' of Eu(III) compared to that observed in the binary system of TC and Eu(III) [Eu3TC]. Transients of Eu(III) emission in aqueous buffer and D2O buffer show that the number of water molecules, coordinated directly to the Eu(III) ion, decreases from 12 in Eu3TC to 2 in the ternary system using oleic acid. The micelle formed by the bent conformation of the unsaturated oleic acid provides a hydrophobic sheet on all sides of Eu3TC complex protecting Eu(III) from interacting with O-H oscillator. The simple biocompatible system could be used for imaging purpose, and biomedical assay.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Luminescence - Volume 160, April 2015, Pages 262-270
نویسندگان
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