Interaction of aconitine with bovine serum albumin and effect of atropine sulphate and glycyrrhizic acid on the binding

► Effect of atropine or glycyrrhizic acid on aconitine-BSA binding. ► UV-vis absorption and fluorescence spectroscopic techniques used. ► Aconitine quenched BSA fluorescence via dynamic quenching with r=2.62 nm. ► Atropine sulphate and glycyrrhizic acid decreased KA and n of aconitine-BSA. ► Support for aconitine detoxification by atropine and glycyrrhizic acid.