کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
540395 | 871311 | 2011 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Nanostructures in protein chips: Effect of print buffer additive and wettability on immobilization and assay performance
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موضوعات مرتبط
مهندسی و علوم پایه
مهندسی کامپیوتر
سخت افزارها و معماری
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Nanostructures of 1 μm period and 180 nm height were fabricated by thermal nanoimprint lithography (thermal NIL) and implemented in protein chips to enhance chip sensitivity. Three epoxy resins which are well characterized materials in lab-on-chip systems and (bio)MEMS and are able to bind proteins via their epoxy function are tested: SU-8 2000.5, EPIKOTE⢠157 and EPON⢠1002F. For improved wettability wetting agents like PEG 200, sorbitol, MCT and oleic acid were added to the protein printing solution. Best chip performance was achieved on EPON⢠1002F nanostructured surfaces, brightest signals when using 0.1% (w/v) PEG in the printing solution.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Microelectronic Engineering - Volume 88, Issue 8, August 2011, Pages 1856-1859
Journal: Microelectronic Engineering - Volume 88, Issue 8, August 2011, Pages 1856-1859
نویسندگان
Claudia Preininger, Ursula Sauer, Mustapha Chouiki, Rainer Schöftner,