کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5413242 1506624 2008 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
On the preferential solvation of drugs and PAHs in binary solvent mixtures
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی تئوریک و عملی
پیش نمایش صفحه اول مقاله
On the preferential solvation of drugs and PAHs in binary solvent mixtures
چکیده انگلیسی
The preferential solvation parameters, i.e., the differences between the local and bulk mole fractions of the solvents in solutions of certain drugs and polycyclic aromatic hydrocarbons (PAHs) are derived from their solubilities in binary solvent mixtures by means of the inverse Kirkwood-Buff integral (IKBI) and the quasi-lattice quasi-chemical (QLQC) methods. The solutes include caffeine, niflumic acid, diazepam, benzocaine, phenacetin, paracetamol, nalidixic acid, anthracene, and tr-stilbene and both aqueous and non-aqueous mixtures are considered. The findings are rationalized in terms of the interactions between the solute and solvents and the solvent components among themselves.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Molecular Liquids - Volume 140, Issues 1–3, 15 April 2008, Pages 61-67
نویسندگان
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