Physicochemical studies of acetaminophen in Water-Peg 400 systems

The characteristics of polarity, permittivity and fluidity of the medium, due to the presence of the polyol, enhance the acetaminophen-PEG 400 associations. These can be established through hydrogen bond and dipole-dipole interactions among the species present in the solution, and are originated by preferential orientations in the directions of the applied electrical field.