Long non-coding RNA HOTAIR promotes ischemic infarct induced by hypoxia through up-regulating the expression of NOX2

High expression of HOTAIR promoted the onset of ischemic infarct induced by hypoxia. Moreover, the finding showed that HOTAIR promoted ischemic infarct induced by hypoxia through regulating NOX2 expression, which could add our understanding of the molecular mechanisms in ischemic infarct.