کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5518289 1543920 2016 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Genomics/technical resourcesComplete genome sequence of Bacillus oceanisediminis 2691, a reservoir of heavy-metal resistance genes
موضوعات مرتبط
مهندسی و علوم پایه علوم زمین و سیارات علوم زمین و سیاره ای (عمومی)
پیش نمایش صفحه اول مقاله
Genomics/technical resourcesComplete genome sequence of Bacillus oceanisediminis 2691, a reservoir of heavy-metal resistance genes
چکیده انگلیسی

Ocean sediments are commonly subject to the pollution of various heavy metals. Intracellular heavy metal concentrations in marine microorganisms should be kept within allowable concentrations. Here, we report redundant heavy metal resistance related genes encoding heavy metal-sensing transcriptional regulators (i.e. cadC), heavy metal efflux pumps, and detoxifying enzymes in the complete genome sequence of Bacillus oceanisediminis 2691. By comparing CadC sequences of strain 2691 with those from other bacterial genomes, we demonstrated that each cadC gene located in the chromosome or plasmid of 2691 cells are similar to those of various near or distant microbes, which might shed light on evolutionary trajectories of redundant heavy metal resistance genes. In application aspects, these diverse heavy metal sensing genes can be harnessed as synthetic biological parts, modules, and devices for the development of heavy metal-specific biosensors. Heavy metal bioremediation technologies or platform cells can be also developed based on the marine genomic information of heavy metal resistance and/or detoxification genes in a bacterial isolate from ocean sediments.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Marine Genomics - Volume 30, December 2016, Pages 73-76
نویسندگان
, , , , ,