کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5545168 | 1555315 | 2017 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Effect of different oral oxytetracycline treatment regimes on selection of antimicrobial resistant coliforms in nursery pigs
ترجمه فارسی عنوان
تاثیر رژیمهای مختلف اکسایت تتراسایکلین خوراکی بر انتخاب کلیفرم های مقاوم به ضد میکروبی در خوک های پرورشگاه
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
چکیده انگلیسی
A major concern derived from using antimicrobials in pig production is the development of resistance. This study aimed to assess the impact of selected combinations of oral dose and duration of treatment with oxytetracycline (OTC) on selection of tetracycline resistant (TET-R) coliforms recovered from swine feces. The work encompassed two studies: 1) OTC 5Â mg/kg and 20Â mg/kg were administered to nursery pigs for 3 and 10Â days, respectively, under controlled experimental conditions, and 2) 10Â mg/kg, 20Â mg/kg and 30Â mg/kg OTC were given to a higher number of pigs for 6, 3 and 2Â days, respectively, under field conditions. Statistical modeling was applied to analyze trends in the proportion of TET-R coliforms. In the experimental study, no statistical difference in proportion of TET-R coliforms was observed between treatments at the end of the trial (day 18) and compared to day 0. In the field study, treatment had a significant effect on the proportion of TET-R bacteria two days after the end of treatment (2dAT) with the regimes “low dose-six days” and “medium dose-three days” yielding the highest and lowest proportions of TET-R strains, respectively. No indication of co-selection for ampicillin- and sulphonamide -R bacteria was observed for any treatment at 2dAT. By the end of the nursery period, the proportion of TET-R bacteria was not significantly different between treatments and compared to day 0. Our results suggest that similar resistance levels might be obtained by using different treatment regimes regardless of the combinations of oral dose-duration of treatment.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Veterinary Microbiology - Volume 208, September 2017, Pages 1-7
Journal: Veterinary Microbiology - Volume 208, September 2017, Pages 1-7
نویسندگان
Ana Herrero-Fresno, Camilla Zachariasen, Nanna Nørholm, Anders Holm, Lasse Engbo Christiansen, John Elmerdahl Olsen,