کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5545452 | 1555325 | 2017 | 33 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Origin and evolution of LX4 genotype infectious bronchitis coronavirus in China
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
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چکیده انگلیسی
We investigated the genomic characteristics of 110 LX4 genotype strains of infectious bronchitis viruses (IBVs) isolated between 1995 and 2005 in China. The genome of these IBVs varies in size from 27596Â bp to 27790Â bp. Most IBV strains have the typical genomic organization of other gamacoronaviruses, however, two strains lacked 3a and 5b genes as a result of a nucleotide change within the start codon in the 3a or 5b genes. Analysis of our 110 viruses revealed that recombination events may be responsible for the emergence of the LX4 genotype with different topologies. Most of these viruses disappeared (before mid-2005) because they were not “fit” to adaptation in chickens. Finally, those of the “fit” viruses (after mid-2005) continued to evolve and have become widespread and predominant in commercial poultry. In addition, few of these viruses experienced recombination with those of the vaccine strains at the 3â² end of the genome.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Veterinary Microbiology - Volume 198, January 2017, Pages 9-16
Journal: Veterinary Microbiology - Volume 198, January 2017, Pages 9-16
نویسندگان
Wenjun Zhao, Mengying Gao, Qianqian Xu, Yang Xu, Yan Zhao, Yuqiu Chen, Tingting Zhang, Qiuling Wang, Zongxi Han, Huixin Li, Lingfeng Chen, Shuling Liang, Yuhao Shao, Shengwang Liu,