کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5585610 1568234 2017 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Distributing signaling proteins in space and time: the province of cytonemes
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شناسی تکاملی
پیش نمایش صفحه اول مقاله
Distributing signaling proteins in space and time: the province of cytonemes
چکیده انگلیسی
During development, cells use specialized filopodia called cytonemes to deploy the signaling proteins that coordinate growth and direct morphogenesis. Cytonemes are dynamic structures that can extend long distances across tissues to either deliver or take up signaling proteins. Signaling proteins transfer between cells at the tips of cytonemes where specific contacts termed morphogenetic synapses form. This review summarizes our current understanding of the roles and functions of cytonemes, and it explores some of the conceptual issues relevant to the cytoneme mechanism of contact-dependent cell-cell signaling.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Genetics & Development - Volume 45, August 2017, Pages 22-27
نویسندگان
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