کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5587626 1568862 2017 18 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effects of BPA on female reproductive function: The involvement of epigenetic mechanism
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
پیش نمایش صفحه اول مقاله
Effects of BPA on female reproductive function: The involvement of epigenetic mechanism
چکیده انگلیسی
Epigenetic modifications are classified as heritable and reversible chemical modifications of chromatin that do not cause changes in DNA sequence. Changes in epigenetic modifications can be caused by exposure to certain environmental factors, such as contaminants like bisphenol A (BPA). Bisphenol A is ubiquitous in the environment and produced in large quantities, and known to have hormone-like activity, whereby disrupting endocrine function. Because of evidence for disruption of sex steroid mediated pathways, there is a concern that BPA could have adverse effects on female reproduction. The purpose of this review is to summarize the effects of BPA on adult female reproduction with focus on epigenetic changes that can be heritable.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: General and Comparative Endocrinology - Volume 245, 1 May 2017, Pages 122-126
نویسندگان
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